SCARS
STRETCH MARKS
UNEVEN SKIN TONE
Bio-Oil® is the world's leading scar and stretch mark product.
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Uses
Scars
Scars
Scars are an integral part of the healing process and result from an overproduction of collagen at the wound site. Scars go through numerous changes as they mature, but they are permanent in nature. Bio-Oil is formulated to help improve the appearance of scars, but it can never remove them.
Bio-Oil should be massaged in a circular motion into the scar, twice daily, for a minimum of 3 months. On new scars, Bio-Oil should be applied only once the wound has healed, and should not be used on broken skin. Results will vary from individual to individual.
Stretch marks
Stretch marks
When the body expands faster than the covering skin, the skin tears, forming a scar as it heals. These scars are visible on the surface of the skin as stretch marks.
The likelihood of developing stretch marks varies according to skin type, race, age, diet and hydration of the skin. Those most prone to stretch marks include pregnant women, body builders, adolescents undergoing sudden growth spurts and individuals who experience rapid weight gain.
Stretch marks are permanent in nature, and although Bio-Oil is formulated to help improve their appearance, it can never remove them.
Bio-Oil should be massaged in a circular motion into the stretch marks, twice daily, for a minimum of 3 months. During pregnancy, it should be applied from the start of the second trimester to areas that are prone to stretch marks such as the abdomen, breasts, lower back, hips, buttocks and thighs. Results will vary from individual to individual.
Uneven skin tone
Uneven skin tone
Uneven skin tone occurs when there is an inconsistent production of melanin by the body. This can be triggered by external causes, such as excessive exposure to the sun or the use of poor quality skin lightening products; or internal causes, such as hormonal fluctuations related to pregnancy, menopause or the use of oral contraceptives. Bio-Oil helps improve the appearance of uneven skin tone.
Bio-Oil should be applied to the affected areas, twice daily, for a minimum of 3 months. Bio-Oil does not contain a sunscreen factor. If using a sunscreen apply once Bio-Oil has been fully absorbed. Results will vary from individual to individual.
Ageing skin
Ageing skin
Wrinkled skin commonly associated with ageing is largely caused by the weakening of the collagen and elastin support system in the skin. Bio-Oil contains numerous ingredients that help to plasticise the skin, making it softer, smoother and more supple, thereby reducing the appearance of wrinkled skin. Bio-Oil also moisturises, which improves the texture, tone and appearance of fine lines and wrinkles.
Bio-Oil should be applied to the affected areas twice daily. Results will vary from individual to individual.
Dehydrated skin
Dehydrated skin
The surface of the skin has an invisible oil layer which acts as a barrier to stop moisture from escaping. In a very dry climate this lipid layer is often unable to cope and too much moisture is drawn out of the skin. Daily bathing or showering may exacerbate this by stripping away the lipid layer due to the astringent effects of soap and water. Bio-Oil supplements the skin’s natural oil layer, helping to restore its barrier function of retaining moisture.
Bio-Oil should be applied twice daily. Results will vary from individual to individual.

Formulation
Formulation
Formulation
The Bio-Oil formulation is a combination of plant extracts and vitamins suspended in an oil base. It contains the breakthrough ingredient PurCellin Oil™, which changes the formulation’s overall consistency, making it light and non-greasy, ensuring that the goodness contained in the vitamins and plant extracts is easily absorbed.
Bio-Oil has undergone safety assessments in accordance with the Regulation of the European Parliament and of the Council on Cosmetic Products. The toxicological profile, chemical structure, level of inclusion and total level of daily exposure of each ingredient used has been assessed and deemed safe for use (including for use by pregnant women).
Ingredients
Ingredients
Botanicals
Calendula Officinalis Flower Extract (Calendula Oil)
Lavandula Angustifolia Oil (Lavender Oil)
Rosmarinus Officinalis Leaf Oil (Rosemary Oil)
Anthemis Nobilis Flower Oil (Chamomile Oil)
Vitamins
Retinyl Palmitate (Vitamin A)
Tocopheryl Acetate (Vitamin E)
Oil base
Paraffinum Liquidum
Triisononanoin
Cetearyl Ethylhexanoate
Isopropyl Myristate
Glycine Soja Oil
Helianthus Annuus Seed Oil
BHT
Bisabolol
Fragrance (Rose)
Parfum
Alpha-Isomethyl Ionone
Amyl Cinnamal
Benzyl Salicylate
Citronellol
Coumarin
Eugenol
Farnesol
Geraniol
Hydroxycitronellal
Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde
Limonene
Linalool
Colour
CI 26100
Manufacture
Manufacture
Bio-Oil is manufactured in accordance with cGMP (current Good Manufacturing Practice) as stipulated by the World Health Organisation. All ingredients are tested for adulteration and microbiological contamination prior to production and a sample from each batch manufactured is laboratory tested and then retained and monitored over a 5-year period.
All Bio-Oil packaging is recyclable and all paper materials are certified to be in accordance with sustainable forest management practices.
No harmful emissions, hazardous waste or wastewater is generated in the production of Bio-Oil.

Clinical trials
Scar study, 2010
Scar study, 2010
Trial centre
proDERM Institute for Applied Dermatological Research, Hamburg, Germany.
Objective
To assess the efficacy of Bio-Oil in improving the appearance of scars.
Sample
Subjects: 36 female participants of varying ethnicities. Age of participants: 18 to 65. Scar ages: newly formed to 3 years old. Scar locations: abdomen, leg, arm, neck, knee, trunk, upper body.
Methodology
Double-blind, randomised and placebo controlled. Subjects had matching scars or a scar large enough to allow a half-half scar application and intra-subject comparison. Product applied twice daily for 8 weeks, no additional massaging performed on the target area. Application performed under supervision at regular intervals. Assessments conducted at 0, 2, 4 and 8 weeks. Different scar parameters as defined in the Patient and Observer Scar Assessment Scale (POSAS) were evaluated.
Result
Bio-Oil is efficacious in improving the appearance of scars. A statistically significant result after only 2 weeks (day 15), evident in 66% of the subjects. After 8 weeks (day 57) 92% of subjects showed an improvement, with the extent of the improvement almost triple that at 2 weeks. A continuous improvement of POSAS over the duration of the study.
Scar study, 2005
Scar study, 2005
Trial centre
Photobiology Laboratory of the Medical University of South Africa.
Objective
To assess the efficacy of Bio-Oil in improving the appearance of scars.
Sample
Subjects: 24 participants, 22 female and 2 male. Age of participants: 18 to 60. Scar ages: newly formed to 3 years old. Scar types: range from minor burns to surgical scars (12 major scars, 14 minor scars - 1 participant had three scar sites).
Methodology
Single-blind (assessor), randomised and controlled. Paired study design allowing for intra-subject comparison. Subjects had matching scars or a scar large enough to allow application to half a scar. Product applied twice daily for 12 weeks to the targeted area. Application performed under supervision at regular intervals. Assessments conducted at 0, 4, 8 and 12 weeks.
Result
Bio-Oil improved the appearance of scars in both objective and subjective assessments. 65% of subjects recorded an improvement in appearance at 4 weeks.
Scar user trial, 2002
Scar user trial, 2002
Trial centre
Ayton-Moon, Somerset, United Kingdom.
Objective
To rate the ability of Bio-Oil to improve the appearance of scars, in an 82-person user trial.
Sample
Subjects: 82 participants including adults and children. Scar ages: newly formed to older than 10 years. Scar types: raised, flat and depressed scars, ranging from minor burns and grazes to surgical scars. Scar locations: various.
Methodology
Product applied 3 times daily for 4 weeks. Participants instructed to massage in a circular motion until product fully absorbed. Interviews conducted at 0, 2 and 4 weeks. Participants rated the improvement they noticed on a scale from 1 - 9 (1 representing ‘no improvement’ and 9 representing ‘much improvement’).
Result
82% of participants recorded an improvement in the appearance of their scars after 4 weeks.
Acne scar study, 2012
Acne scar study, 2012
Trial centre
Dept. of Dermatology, Peking University First Hospital, Beijing, China.
Objective
An exploratory study to assess the efficacy of Bio-Oil in improving the appearance of facial acne scars on Chinese subjects.
Sample
Subjects: 44 Chinese subjects with newly formed acne scars on the face (<1 year old). Bio-Oil treatment cell included 32 subjects and the no treatment cell included 12 subjects. Age of participants: 14 to 30.
Methodology
Randomised, controlled, efficacy grader-blinded. Subjects participated in an initial screening evaluation followed by a 1-week washout period. Product applied twice daily for 10 weeks. Application performed under supervision at regular intervals. Assessments conducted at 0, 4, 8 and 10 weeks included the following: Global scarring score (GSS) assessment by the investigator, measurement of acne scar colour / redness using a chromameter, measurement of sebum levels using a sebumeter, documentation of number of comedones and inflammatory lesions by a dermatologist. Subjects also completed self-assessment questionnaires at each visit.
Result
The best result of the clinical grading was in Bio-Oil’s ability to reduce the erythema or redness of macular (flat) acne scars, with the overall skin becoming brighter. Results of the self-assessment questionnaire showed that more than 84% of subjects experienced an improvement in the overall condition of their acne scars and more than 90% experienced an improvement in scar colour. Acne count and sebum measurement results showed that using Bio-Oil does not cause or aggravate acne or increase sebum secretion.
Stretch mark study, 2010
Stretch mark study, 2010
Trial centre
proDERM Institute for Applied Dermatological Research, Hamburg, Germany.
Objective
To assess the efficacy of Bio-Oil in improving the appearance of stretch marks.
Sample
Subjects: 38 female participants of varying ethnicities. Age of participants: 18 to 65. Stretch mark causes: various (post pregnancy, weight gain or adolescent growth spurt). Stretch mark locations: abdomen, thigh and hips.
Methodology
Double-blind, randomised and placebo controlled. Subjects had matching stretch marks or a stretch mark large enough to allow a half-half stretch mark application and intra-subject comparison. Product was applied twice daily for 8 weeks, no additional massaging performed on the target area. Application performed under supervision at regular intervals. Assessments conducted at 0, 2, 4 and 8 weeks. Different scar parameters as defined in the Patient and Observer Scar Assessment Scale (POSAS) were evaluated.
Result
Bio-Oil is efficacious in improving the appearance of stretch marks. A statistically significant result after only 2 weeks (day 15), evident in 95% of the subjects. After 8 weeks (day 57) 100% of subjects showed an improvement, with the extent of the improvement more than double that at 2 weeks. A continuous improvement of POSAS over the duration of the study.
Stretch mark study, 2005
Stretch mark study, 2005
Trial centre
Photobiology Laboratory of the Medical University of South Africa.
Objective
To assess the efficacy of Bio-Oil in improving the appearance of stretch marks.
Sample
Subjects: 20 female participants. Age of participants: 18 to 55. Stretch mark location: abdomen.
Methodology
Single-blind (assessor), randomised and controlled. Paired study design allowing for intra-subject comparison. Subjects had bilateral abdominal stretch marks, enabling half-abdomen study design. Product applied twice daily for 12 weeks to the targeted area. Application performed under supervision at regular intervals. Assessments conducted at 0, 4, 8 and 12 weeks.
Result
Bio-Oil improved the appearance of stretch marks in both objective and subjective assessments. 50% of subjects recorded an improvement in appearance at 8 weeks.
Uneven skin tone study, 2011
Uneven skin tone study, 2011
Trial centre
Thomas J. Stephens & Associates, Inc., Texas, United States of America.
Objective
To evaluate the efficacy of Bio-Oil in improving the appearance of uneven skin tone and mottled pigmentation when used by women with mild to moderate photodamaged (ageing) skin on the face and neck.
Sample
Subjects: 67 female participants (of varying ethnicities) with clinically determined mild to moderate photodamage on the face and neck. Bio-Oil treatment cell included 35 subjects and the no treatment cell included 32 subjects. Age of participants: 30 to 70.
Methodology
Randomised, controlled, efficacy grader-blinded. Subjects participated in an initial screening evaluation followed by a 1-week washout period. Product applied to the face and neck twice daily for 12 weeks. Application performed under supervision at baseline visit. Clinical evaluations conducted at 0, 2, 4, 8 and 12 weeks. Subjects were clinically graded separately on the face and neck for uneven skin tone and mottled pigmentation.
Result
Bio-Oil is efficacious in improving the appearance of uneven skin tone and mottled pigmentation in photodamaged (ageing) skin. After 4 weeks a statistically significant result was achieved for both parameters on the face and neck. After 12 weeks 86% of subjects in the Bio-Oil treatment cell showed a statistically significant improvement in uneven skin tone on the face, 71% of subjects in mottled pigmentation on the face, 69% in uneven skin tone on the neck and 60% in mottled pigmentation on the neck.
Uneven skin tone study, 2005
Uneven skin tone study, 2005
Trial centre
Photobiology Laboratory of the Medical University of South Africa.
Objective
To assess the efficacy of Bio-Oil in improving the appearance of uneven skin tone.
Sample
Subjects: 30 female participants of varying ethnicities. Age of participants: 18 to 55. Pigmentation type: facial melasma.
Methodology
Single-blind (assessor), randomised and controlled. Paired study design allowing for intra-subject comparison. Subjects had bilateral pigmentation, enabling half-face/neck study design. Product applied twice daily for 12 weeks to the targeted area. Application performed under supervision at regular intervals. Assessments conducted at 0, 4, 8 and 12 weeks.
Result
Bio-Oil improved the appearance of uneven skin tone in both light and dark skin types. 93% of subjects recorded an improvement in appearance at 6 weeks. Clinician noted an equal improvement in both light and dark skin types from week 0 to 8. Clinician noted more improvement in dark skin types from week 8 to 12.
Ageing skin study, 2011
Ageing skin study, 2011
Trial centre
Thomas J. Stephens & Associates, Inc., Texas, United States of America.
Study 1: face & neck
Objective
To evaluate the efficacy of Bio-Oil when used by women with mild to moderate photodamaged (ageing) skin on the face and neck.
Sample
Subjects: 67 female participants (of varying ethnicities) with clinically determined mild to moderate photodamage on the face and neck. Bio-Oil treatment cell included 35 subjects and the no treatment cell included 32 subjects. Age of participants: 30 to 70.
Methodology
Randomised, controlled, efficacy grader-blinded. Subjects participated in an initial screening evaluation followed by a 1-week washout period. Product applied to the face and neck twice daily for 12 weeks. Application performed under supervision at baseline visit. Clinical evaluations conducted at 0, 2, 4, 8 and 12 weeks. Subjects were clinically graded separately on the face and neck for the following efficacy parameters: overall appearance, fine lines, coarse wrinkles, mottled pigmentation, uneven skin tone, visual roughness/smoothness, tactile roughness/smoothness, firm appearance, and clarity (dullness).
Result
Bio-Oil is efficacious in improving the overall appearance of photodamaged (ageing) skin on the face and neck. After 8 weeks a statistically significant result was achieved for all clinically graded efficacy parameters. After 12 weeks 94% of subjects in the Bio-Oil treatment cell showed a statistically significant improvement in overall appearance on the face and 80% of subjects showed a statistically significant improvement in overall appearance on the neck.
Study 2: body
Objective
To evaluate the efficacy of Bio-Oil when used on the décolletage, lower leg and arm skin by women with mild to moderate photodamaged (ageing) skin.
Sample
Subjects: 67 female participants (of varying ethnicities) with clinically determined mild to moderate photodamage on the face and neck. Bio-Oil treatment cell included 35 subjects and the no treatment cell included 32 subjects. Age of participants: 30 to 70.
Methodology
Randomised, controlled, efficacy grader-blinded. Subjects participated in an initial screening evaluation followed by a 1-week washout period. Product applied to the décolletage, lower legs and arms twice daily for 12 weeks. Application performed under supervision at baseline visit. Clinical evaluations conducted at 0, 2, 4, 8 and 12 weeks. Subjects were clinically graded separately on the décolletage, lower legs and arms for the following efficacy parameters: overall appearance, crêpey texture, dryness/scaling, visual roughness/smoothness, and tactile roughness/smoothness.
Result
Bio-Oil is efficacious in improving the overall appearance of photodamaged (ageing) skin on the body. After 4 weeks a statistically significant result was achieved for all clinically graded efficacy parameters. After 12 weeks 89% of subjects in the Bio-Oil treatment cell showed a statistically significant improvement in overall appearance of the décolletage, lower legs and arms.
Dehydrated skin study, 2011
Dehydrated skin study, 2011
Trial centre
Photobiology Laboratory of the Medical University of South Africa.
Study 1
Objective
To assess the effect of a single application of Bio-Oil to improve stratum corneum (SC) barrier function and hydration.
Sample
Subjects: 40 female participants of varying ethnicities. Test site: test products applied to the volar forearm of all subjects.
Methodology
Assessment of skin hydration with a Corneometer as the primary measure, assessment of barrier function with a Vapometer as a secondary measure. Panellists washed their forearms with soap 2 hours before measurements were taken. Baseline instrumental measurements were taken. Bio-Oil and a reference oil were then applied to separate sites on the volar forearm of all subjects. Measurements were taken again immediately after product application as well as 2 hours later, before and after wiping the products off. A control untreated site was also measured at all time points.
Result
After immediate application, both oils reduced transepidermal water loss (TEWL) compared to the no treatment control. Increased skin capacitance values at the 2 hour pre-wipe time point indicated increased skin hydration for both oils. Two hours later, after wiping the oils from the skin’s surface, Bio-Oil showed further increased TEWL values compared to the reference oil, indicating increased moisture release and therefore increased skin hydration.
Study 2
Objective
To assess the effect of twice daily application of Bio-Oil for moisturisation performance and relief of dry skin.
Sample
Subjects: 25 female Caucasian participants. Test site: test products applied to the outer, lower leg of all subjects.
Methodology
Soap was used to induce dry skin over a 7 day period. Bio-Oil and a reference oil were applied twice daily. Skin assessments were made on days 1 and 3. Visual evaluations were performed by a trained visual evaluator using a 2x magnifying lamp. A control untreated site was also evaluated at all time points.
Result
Both Bio-Oil and the reference oil improved skin dryness compared with the no treatment control. Bio-Oil was statistically superior on day 3. Significant improvements in visual appearance of skin sites treated with Bio-Oil confirmed its effectiveness in relieving dry skin.
Acnegenic test, 2006
Acnegenic test, 2006
Trial centre
Future Cosmetics, Pretoria, South Africa.
Objective
To test whether Bio-Oil is likely to cause acne and comedones (pimples).
Sample
Subjects: 21 participants, 17 female and 4 male of varying ethnicities, 50% prone to acne.
Methodology
Randomised and controlled. Product applied twice daily for 28 days. 3 areas evaluated: untreated area (negative control), area to which Bio-Oil was applied, and area to which acetylated lanolin alcohol was applied (positive control - a known acnegenic product). Test products applied to the upper back (scapular) region.
Result
Bio-Oil was found to be non-acnegenic and non-comedogenic. Area to which Bio-Oil was applied showed no significant difference to the untreated area. Positive control induced acne.
Sensitive skin test, 2006
Sensitive skin test, 2006
Trial centre
Future Cosmetics, Pretoria, South Africa.
Objective
To test whether Bio-Oil causes skin irritancy on subjects with sensitive skin.
Sample
Subjects: 21 participants. Age of participants: 18 to 65. Selection criteria: Subjects with known sensitive skin were selected and exposed to a positive control (lactic acid) to verify their sensitive skin status.
Methodology
Randomised and controlled. 3 areas were evaluated: area to which deionised water was applied (negative control), area to which Bio-Oil was applied, and area to which Sodium Lauryl Sulfate 1% solution was applied (positive control - a known skin irritant). Test products applied via a patch to the volar forearm and removed after 24 hours. Skin evaluated and reactions noted at 24, 48, 72 and 96 hours after application. Dermatologist present during the evaluations. Skin reactions rated on a scale from 0 – 4 (with 0 being no response and 4 being fiery redness).
Result
Bio-Oil was found to be a non-irritant product for subjects with sensitive skin. No subjects experienced any adverse reactions to Bio-Oil. Bio-Oil had an average reaction value of 0.03 over the period of 96 hours. Bio-Oil performed better than deionised water (negative control).
Absorption study, 2011
Absorption study, 2011
Trial centre
proDERM Institute for Applied Dermatological Research, Hamburg, Germany.
Study 1
Objective
To assess the rate of absorption of Bio-Oil after standardised application and rubbing in.
Sample
Subjects: 22 trained raters (21 female and 1 male). Test site: test products applied to the volar forearm of all raters.
Methodology
Double-blind, randomised and controlled. Bio-Oil and a reference oil were applied to assigned test areas on the volar forearms of raters. Raters performed 100 cyclic movements at a defined speed. Raters then rated the absorption of the products on a 5-point scale from ‘very slow absorbing’ to ‘very fast absorbing’. Sebumeter measurements, to assess the amount of oil on the skin, were taken at two time points - before application and two minutes after product application.
Result
The absorbency of Bio-Oil into the skin was assessed as ‘very fast’ or ‘fast’ by the majority (77.3%) of trained raters. This was verified through instrumental measurement with sebumeter readings at the second time point showing that the amount of Bio-Oil left on the skin was significantly lower than compared with the reference oil.
Study 2
Objective
To assess the rate of absorption of Bio-Oil after standardised application and rubbing in.
Sample
Subjects: 100 participants (97 female and 3 male). Test site: test products applied to the volar forearm of all participants.
Methodology
Double-blind, randomised and controlled. Bio-Oil and a reference oil were applied to assigned test areas on the volar forearms of participants. Participants rubbed in the test product for 1 minute each. Participants then rated the absorption of the products on a 5-point scale from ‘very slow absorbing’ to ‘very fast absorbing’.
Result
The absorbency of Bio-Oil into the skin was assessed as ‘very fast’ or ‘fast’ by the majority (72%) of participants.
Occlusivity study, 2008
Occlusivity study, 2008
Trial centre
Trial conducted by Prof. Dr. J Wiechers at Rigano Laboratories, Milan, Italy.
Objective
To evaluate whether Bio-Oil demonstrates a similar occlusivity level to vernix caseosa. (Vernix caseosa, the creamy-white and viscous biofilm that envelopes a baby while it is in the womb, is widely considered by cosmetic scientists as the ‘gold standard’ in skin moisturisation because of its ideal occlusivity level.)
Methodology
Known quantities of water were placed in beakers covered with a semi-permeable membrane called Vitro-Skin™, which mimics the surface properties of human skin. Vernix caseosa and Bio-Oil were applied to the membrane and the rate of water loss from the beaker was measured over time. This was compared with the rate of water loss without any product on the membrane. The water vapour transfer rate for each product was calculated and expressed in g/m2/h.
Result
Bio-Oil demonstrated a very similar occlusivity level to vernix caseosa, with Bio-Oil registering 23.5 and vernix caseosa 27.2.

Accolades
Awards Most recommended
Product most recommended by doctors / pharmacists / midwives for scars and stretch marks
Australia, Doctor survey (ACA Research HCP Study, 2017)
Australia, Pharmacist survey (ACA Research HCP Study , 2017)
Canada, Doctor survey (Rogers Connect Market Research, 2017)
Canada, Pharmacist survey (Rogers Connect Market Research, 2017)
Germany, Pharmacist survey (BVDA / German Pharmacist Association, 2015)
Ireland, Pharmacist survey (3 Gem, 2015)
Italy, Midwife survey (Millward Brown, 2014)
Kenya, Pharmacist survey (Consumer Insight, 2015)
New Zealand, Doctor survey (Colmar Brunton, 2016)
New Zealand, Midwife survey (Colmar Brunton, 2016)
South Africa, Doctor survey (IPSOS, 2018)
South Africa, Gynaecologist survey (IPSOS, 2018)
South Africa, Midwife survey (IPSOS, 2018)
South Africa, Pharmacist survey (IPSOS, 2018)
United Kingdom, Pharmacist survey (3 Gem, 2018)
Zimbabwe, Doctor survey (Marketers Association of Zimbabwe, 2016)
Zimbabwe, Midwife survey (Marketers Association of Zimbabwe, 2016)
Zimbabwe, Pharmacist survey (Marketers Association of Zimbabwe, 2016)
No. 1 selling
No.1 selling scar and stretch mark product
Australia (Aztec Segment and item list as defined by Aspen Pharmacare, based on AU Grocery & Pharmacy Scan combined data within Hand & Body Skin Care Database. September, 2017)
Belgium (IMS Health Data Q3, 2018 )
Botswana (Medswana (Pty) Ltd, 2016)
Canada (Nielsen MarketTrack. Specialty Creams, Lotions and Scar Treatments. National Grocery, Drug + Mass, 52 weeks ending Feb 3, 2018)
Finland (Pharmacy data and GFT retail data, value sales, 2016)
Germany (Nielsen IMS Health)
Hungary (IMS Health Pharmacy Survey Q1, 2016)
Ireland (Nielsen ScanTrack ROI. Body Lotions and Treatments, MAT value sales, 2015)
Italy (IMS Health. Pharmacy + Parapharmacy + GDO Corner. Reconstructed Classes Anti-Stretch Marks (82F2A) + Scars (46A3). Sales by volume, September 2017)
Kenya (Consumer Insight, 2015)
Liechtenstein (IMS Health GmbH - Pharma Trend, Units & Sales Value, Sept 2017)
Malaysia (Nielsen, Scar & Stretch Mark, PM Drugstore/Pharmacy, January - June 2017)
Namibia (Geka Pharma (Pty) Ltd 2016 and Nampharm 2016)
Netherlands (IRI, YTD 52 2016)
New Zealand (IRI, National Combined MAT, October 2015)
Poland (IQVIA Pharma Scope. Firming & Anti-stretch mark products, 2017)
Portugal (hmR, Pharmacy only, Oct 2018)
Singapore (Nielsen, Scar & Stretch Mark, PM Drugstore/Pharmacy, 2016)
South Africa (Nielsen, Total Value ranking 52 week period ending 31 Jan 2018)
Swaziland (Swazi Pharm Wholesalers (Pty) Ltd, 2016)
Sweden (Nielsen Scanningdata, HPC, Other Skincare, Scars/Stretchmarks, MAT W40, 2018)
Switzerland (IMS Health GmbH - Pharma Trend, Units & Sales Value, Sept 2017)
Ukraine (PharmStandard)
United Kingdom (IRI HBA/OTC, 52 w/e 8th October, 17)
Zimbabwe (Marketers Association of Zimbabwe, May 2016)

Availability
United Kingdom
Recommended retail price
£ 9.99 (60ml)
£ 16.99 (125ml)
£ 22.99 (200ml)

Available at
Pharmacies
Boots
Superdrug
Lloyds pharmacy
Tesco
Asda
Morrisons
Sainsbury's
Waitrose
Amazon



DRY SKIN
Pioneering new technology for dry skin sufferers.
Bio-Oil home Bio-Oil home
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Dry skin user trial, 2017
Trial centre
Ayton Global Research, Somerset, United Kingdom.
Objective
To assess the performance of Bio-Oil Dry Skin Gel in the alleviation of dry skin on the body, in a 102-person user trial.
Sample
Subjects: 102 female participants with self-assessed “Very Dry” skin on the body. Age of participants: 18 and over.
Methodology
A two-week, single-placement, in-home user trial. Participants were instructed to apply product daily to clean, dry skin. Two short questionnaires were completed: the first after initial application and the second after two weeks of using the product.
Result
Application: 94% of participants agreed that “the product is easy to apply” and 96% of participants agreed that “a little goes a long way”.
Absorption: 83% of participants agreed that “the product absorbs easily into the skin”
Hydration: 92% of participants agreed that “the product leaves skin feeling immediately moisturised”; 80% of participants agreed “their skin felt moisturised throughout the day”; 86% of participants agreed that “their dry skin improved over the course of the two-week period”; and, 85% of participants agreed that “their skin looks better than it did at the beginning of the two-week period”.
Overall: 62% of participants agreed that “the product is better than anything they have used before for dry skin”.
Overview
Bio-Oil® Dry Skin Gel is a new way to treat dry skin. Traditional dry skin products such as creams, lotions and body butters are made primarily from water. Most of this water simply evaporates when coming into contact with your skin. It’s often what causes the cold sensation that you feel when applying these products. Bio-Oil® Dry Skin Gel is made from oil, so feels “warm” on application. In a user trial conducted on dry skin sufferers, the majority said it was better than anything they had used before for dry skin.

Ingredients
Paraffinum Liquidum, Isopropyl Palmitate, Triisononanoin, Cetearyl Ethylhexanoate, Glycerin, Butyrospermum Parkii Butter, Aqua, Isopropyl Myristate, Urea, Caprylic/Capric Triglyceride, Isostearyl Isostearate, C26-28 Alkyl Dimethicone, Sodium Lactate, Gluconolactone, Sodium PCA, Sodium Hyaluronate, Octyldodecyl PCA, Sucrose Laurate, Sucrose Stearate, Lactic Acid, Lanolin, Butylene Glycol, Dimethicone/Vinyl Dimethicone Crosspolymer, Bisabolol, Helianthus Annuus Seed Oil, Silica, Glycine Soja Oil, BHT, Retinyl Palmitate, Tocopheryl Acetate, Niacinamide, Linoleic Acid, Linolenic Acid, Tocopherol, Anthemis Nobilis Flower Oil, Calendula Officinalis Extract, Rosmarinus Officinalis Leaf Oil, Lavandula Angustifolia Oil, Parfum, Citronellol, Farnesol, Limonene, Linalool, CI 17200.

Clinical trials
Moisture efficacy trial, 2018
Moisture efficacy trial, 2018
Trial centre
Thomas J. Stephens & Associates, Inc., Texas, United States of America.
Objective
To assess the moisturising efficacy of Bio-Oil Dry Skin Gel.
Sample
Subjects: 28 female particpants (of whom 1 with Fitzpatrick skin type I, 13 with skin type II and 14 with skin type III). Age of participants: 29 to 65.
Methodology
Split-body, evaluator-blinded, randomised, controlled clinical trial. A one-week dry down period was followed by a two-week treatment period and a three-day regression period. During the two-week treatment period subjects applied Bio-Oil Dry Skin Gel to the assigned lower leg, the opposite leg remained untreated. Clinical evaluations were conducted at baseline and days 2, 4, 7, 9, 11 and 14 and on regression days 1, 2 and 3. Subjects were clinically graded for dryness (on a scale from 0 – 5). Bioinstrumentation measurement of skin hydration was by Corneometer and SKICON. Bioinstrumentation measurement of transepidermal water loss (TEWL), as an indicator of barrier function, was by Tewameter.
Result
Compared to the untreated side, Bio-Oil Dry Skin Gel showed statistically significant improvements in clinical grading of dryness, SKICON measurements and Corneometer measurements, at all time points; and in Tewameter measurements, at treatment day 14 and regression day 3. For clinical grading of dryness statistically significant improvements were evident in 82% of subjects after only two days. After two weeks 100% of subjects showed a statistically significant result, with the extent of the improvement almost triple that at day 2. Three days after treatment was stopped 93% of subjects had maintained a statistically significant improvement compared to the start of the study.
Dry skin user trial, 2017
Dry skin user trial, 2017
Trial centre
Ayton Global Research, Somerset, United Kingdom.
Objective
To assess the performance of Bio-Oil Dry Skin Gel in the alleviation of dry skin on the body, in a 102-person user trial.
Sample
Subjects: 102 female participants with self-assessed “Very Dry” skin on the body. Age of participants: 18 and over.
Methodology
A two-week, single-placement, in-home user trial. Participants were instructed to apply product daily to clean, dry skin. Two short questionnaires were completed: the first after initial application and the second after two weeks of using the product.
Result
Application: 94% of participants agreed that “the product is easy to apply” and 96% of participants agreed that “a little goes a long way”.
Absorption: 83% of participants agreed that “the product absorbs easily into the skin”
Hydration: 92% of participants agreed that “the product leaves skin feeling immediately moisturised”; 80% of participants agreed “their skin felt moisturised throughout the day”; 86% of participants agreed that “their dry skin improved over the course of the two-week period”; and, 85% of participants agreed that “their skin looks better than it did at the beginning of the two-week period”.
Overall: 62% of participants agreed that “the product is better than anything they have used before for dry skin”.
Sensitive skin test, 2017
Sensitive skin test, 2017
Trial centre
proDERM Institute for Applied Dermatological Research, Hamburg, Germany.
Objective
To assess the potential of Bio-Oil Dry Skin Gel to cause skin irritation.
Sample
Subjects: 31 participants (26 female and 5 male), thereof 52% with sensitive skin according to self-estimation, 26% with type IV allergy (excepting cosmetic ingredients) and 48% with atopy. Age of participants: 20 to 70.
Methodology
Randomised and controlled. Three areas were evaluated: area to which demineralised water was applied (negative control), area to which Bio-Oil Dry Skin Gel was applied, and area to which Sodium Dodecyl Sulfate (SDS) 1% solution was applied (positive control – a known skin irritant). Test products were applied once on the back for a period of 24 hours using an epicutaneous patch test system. Visual evaluation to assess primary skin irritation was performed by a trained grader 15 minutes after removal of the patches, and then 24 hours and 48 hours after patch removal. Skin reactions were rated on a scale from 0 – 4 (with 0 being no response and 4 being a very red and inflamed response).
Result
No subjects experienced any adverse reactions to the test product and scores were the same as for the negative control, with a visual score of 0 (zero) recorded for all subjects at all time points. The skin tolerability of Bio-Oil Dry Skin Gel with respect to irritancy was therefore deemed to be “very good”.
Non-comedogenic study, 2018
Non-comedogenic study, 2018
Trial centre
proDERM Institute for Applied Dermatological Research, Hamburg, Germany.
Objective
To assess the potential of Bio-Oil Dry Skin Gel to form comedones (pimples).
Sample
Subjects: 24 participants with acne prone skin (17 female and 7 male). Age of participants: 24 to 56.
Methodology
Randomised and controlled. The test product (under occlusion) and two negative controls (untreated area (A) and untreated but occluded area (B)) were randomly allocated to three test areas on the acne prone region of the upper back. Test product was applied to the same test area three times per week over four weeks (12 applications in total). At the end of the study, one Skin Surface Biopsy (SSB) was taken from each of the test areas, using the method of Marks and Dawber. The presence of enlarged microcomedones was evaluated in an evaluator-blinded manner using the ranking scales of Mills and Kligman.
Result
Bio-Oil Dry Skin Gel was found to be non-comedogenic, performing significantly better than both negative controls.
Occlusivity study, 2018
Occlusivity study, 2018
Trial centre
Rigano Laboratories, Milan, Italy.
Objective
To experimentally determine the occlusivity of Bio-Oil Dry Skin Gel and thereby its ability to help the skin to retain moisture by reducing transepidermal water loss (TEWL).
Methodology
Known quantities of water were placed in beakers covered with a semi-permeable membrane called Vitro-Skin™, which mimics the surface properties of human skin. Product was applied to the membrane and the rate of water loss from the beakers was measured over time. This was compared with the rate of water loss from control beakers, without any product on the membrane.
Result
The water vapour transmission rate (WVTR) test methodology is a standard test for measuring the occlusivity of products. A reduction in the WVTR value indicates that a particular formulation is occlusive. Bio-Oil Dry Skin Gel was shown to reduce the WVTR values statistically compared to the untreated control when applied to the Vitro-Skin™ membrane, suggesting that Bio-Oil Dry Skin Gel will help the skin to retain moisture.