කැළැල්
සම ඇදිමෙන් පසුව ශේෂවු ඉරි සලකුණු
සමේ වර්ණයේ අසමාකාර බව
Bio Oil ® ලෝකයේ ප්‍රමුඛ කැළැල් සහ සම ඇදීමේ සලකුණු නිෂ්පාදනය
Bio-Oil home Bio-Oil home


කැළැල්
තුවාලයක් සනීප වීමේදී කැළලක් හට ගැනීම සාමාන්‍ය දෙයක් වුවත් ඇත්තෙන්ම කැළලක් හට ගන්නේ කොලැජන් අධි නිෂ්පාදනයේ ප්‍රථිපලයක් ලෙසිනි. කැළලක් මුහුකුරා යාමේදී විවිධාකාර වෙනස් වීම් වලට භාජනය වේ. නමුත් ඒවා ස්වාභාවයෙන් නිත්‍යය. Bio Oil එක ක්‍රමවත්ව සාදා ඇත්තේ කැළැල් වල පෙනුම යහපත් කිරීමටය. නමුත් සම්පූර්ණයෙන්ම ඉවත් කළ නොහැක.
Bio Oil දවසකට දෙසැරයක් කැළැල තිබෙන ස්ථානයට වක්‍රාකාරව සම්භාහනය කරන්න. අඩුම වශයෙන් මාස තුනක්. අළුත් කැළැල් වලට Bio Oil ආලේප කරන්නේ තුවාලය සනීප වූ පසුව හා කැඩුනු චර්මය මත ආලේප නොකළ යුතුය. ප්‍රතිපලය එක් එක් පුද්ගලයාගේ සමේ ස්වභාවය අනුව වෙනස් විය හැක.
භාවිතය
කැළැල්
කැළැල්
තුවාලයක් සනීප වීමේදී කැළලක් හට ගැනීම සාමාන්‍ය දෙයක් වුවත් ඇත්තෙන්ම කැළලක් හට ගන්නේ කොලැජන් අධි නිෂ්පාදනයේ ප්‍රථිපලයක් ලෙසිනි. කැළලක් මුහුකුරා යාමේදී විවිධාකාර වෙනස් වීම් වලට භාජනය වේ. නමුත් ඒවා ස්වාභාවයෙන් නිත්‍යය. Bio Oil එක ක්‍රමවත්ව සාදා ඇත්තේ කැළැල් වල පෙනුම යහපත් කිරීමටය. නමුත් සම්පූර්ණයෙන්ම ඉවත් කළ නොහැක.
Bio Oil දවසකට දෙසැරයක් කැළැල තිබෙන ස්ථානයට වක්‍රාකාරව සම්භාහනය කරන්න. අඩුම වශයෙන් මාස තුනක්. අළුත් කැළැල් වලට Bio Oil ආලේප කරන්නේ තුවාලය සනීප වූ පසුව හා කැඩුනු චර්මය මත ආලේප නොකළ යුතුය. ප්‍රතිපලය එක් එක් පුද්ගලයාගේ සමේ ස්වභාවය අනුව වෙනස් විය හැක.
සම ඇදිමෙන් පසුව ශේෂවු ඉරි සලකුණු
සම ඇදිමෙන් පසුව ශේෂවු ඉරි සලකුණු
සම මතුපිට ආවරණයට වඩා වැඩි වේගයකින් මස්පිඩු වර්දනයත් සමගම සමේ ඉරීමක් සිදුවීමට පුළුවන. මෙම ඉරීම ටික කලකට පසු සම මතුපිට ඉරි ඇඳීම් හැටියට එහෙමත් නැතිනම් ස්ට්‍රෙච් මාර්කස් හැටියට දිස් වේ .
බොහෝ දුරට සමේ ඉරි ඇඳීම් ඇතිවීමට හේතු කාරක වන්නේ සමේ ස්වාභාවය, ජාතිය , වයස, පෝෂණය සහ සමේ තෙතමනය යන කරුණුය. බොහෝ වෙලාවට ඉරි ඇඳීම් වලට ගොදුරු වන්නේ ගැබිණි මව්වරුන් , කාය වර්ධනය කරන්නන් , වර්ධන අවදියේ සිටින යෞවන යෞවනියන් සහ සීග්‍රයෙන් ශරීර වර්ධනයක් ඇති අයය.
ස්වභාවයෙන් සම ඇදීමේ සළකුණු ස්ථීරය. එමෙන්ම Bio Oil සාදා ඇත්තේ හොඳ පෙණුමක් දීමටය. නමුත් සම්පූර්ණයෙන්ම ඉවත් කල නොහැක.
Bio Oil, සම ඇදීමේ සළකුණු මත ආලේප කර වක්‍රාකාරව සම්භාහනය කරන්න, මෙය දවසකට දෙසැරයක් අඩුම තරමින් මාස තුනක්වත් භාවිතා කරන්න. ගර්භනී අවධියේදී, දෙවන කාර්තුව ආරම්භයේ සිට උදරය, පියයුරු, තුනටිය , උකුල්, තට්ටම් සහ කලවා වැනි සම ඇදීමේ සලකුණු ඇතිවිය හැකි ස්ථාන වල අලේප කරන්න. එක් එක් පුද්ගලයා හැටියට ප්‍රතිපල වෙනස් විය හැක.
සමේ වර්ණයේ අසමාකාර බව
සමේ වර්ණයේ අසමාකාර බව
සමේ වර්ණයේ අසමාකාර බව ඇතිවැන්නේ ශරීරය තුල අසාමාන්‍ය ලෙස (අඩුවෙන් සහ වැඩියෙන් ) මෙලනින් නිපදවීමෙනි. මෙය විය හැක්කේ පිටස්තර හේතුවලටය. එනම් වැඩිපුර හිරු එලියට අනාවරණය වීම හෝ දුර්වල ගණයේ චර්මය බැබළෙන නිෂ්පාදන භාවිතය හෝ අභ්‍යන්තර හේතු එනම් ගර්භණි අවස්ථාවලදී හෝමෝන අඩුවැඩිවීම, ආර්තවභරණය හෝ ගැබ්ගෙල මුඛෙන් ගැබ්ගැනීම වැලැක්වීම. Bio Oil සමේ වර්ණයේ අසමාකාර බවේ පෙනුම යහපත් කරයි.
Bio Oil දවසකට දෙවරක් අවශ්‍ය තැන්වල අඩුම වශයෙන් මාස තුනක්වත් ආලේප කරන්න. Bio Oil හිරු එළියෙන් ආරක්‍ෂා නොකරයි. ඔබ හිරු එළියට ආරක්ෂිතයක් භාවිතා කරනවා නම් Bio Oil සමට සම්පූර්ණයෙන් අවශෝෂණය කල පසු ආලේප කරන්න. ප්‍රතිපලය එක් එක් පුද්ගලයා හැටියට වෙනස් විය හැක.
වයස්ගත සම
වයස්ගත සම
රැලි වැටුන සමක් ඇතිවන්නේ වයස සමග වුවත් එහි මුලික හේතුව වන්නේ සමට උපකාරී වන කොලැජෙන් සහ ඉල්ස්ටින් දුර්වල වීමය. සම මෙලෙක් කිරීම සඳහා Bio Oil වල නොයෙකුත් දේ අඩංගුය. එම නිසා සම සිනිදු වීම, සුමට වීම සහ සුකුමාර වීම මගින් සමේ රැලි වැටීමේ ප්‍රවනතාව අඩුවේ. තවද Bio Oil මගින් සමේ තෙතමනය සහ ස්වභාවය දියුණු කරන අතර රැලි වැටීමේ රේඛාවල විලාසය අඩු කරයි.
Bio Oil අවශ්‍ය ස්ථාන වල දවසකට දෙවරක් ආලේප කරන්න. ප්‍රතිපල එක් එක් පුද්ගලයා හැටියට වෙනස් විය හැක.
විජලනය වූ සම (වියලි සම)
විජලනය වූ සම (වියලි සම)
සම මතුපිට නොපෙනෙන තෙල් තට්ටුවක් ඇත. මෙය තෙතමනය වාෂ්ප වීමට මායිමක්ව ඇත. වියළි දේශ ගුණය ඇති කාලවල මෙම තෙල් තට්ටුවට වාෂ්ප වීම දරා ගත නොහැක.වැඩිපුර තෙත වාෂ්ප වීම සිදුවෙයි. දිනපතා නෑම හෝ ඇඟසේදීම සහ සබන් හා වතුර භාවිතයෙන් තෙල් තට්ටුවට හානිකර වේ. Bio-Oil සමේ ස්වාභාවික තෙල්වලට අතිරේකයකි. එය සමේ තෙතමතය ආරක්ෂා කිරීම ප්‍රකෘතීමත් කරයි.
Bio Oil දවසකට දෙවරක් ආලේප කරන්න. ප්‍රතිපල එක් එක් පුද්ගලයා හැටියට වෙනස් විය හැක.

සංයෝගය
සංයෝගය
සංයෝගය
BIO OIL යනු තෙල් වල බහලු විටමින් සහ ශාක සාර අඩංගු මිශ්‍රනයකි. එහි විශේෂ සොයාගැනීමක් වන Purecilline Oil අඩංගු වන අතර මෙය සංයෝගයේ සාන්ද්‍රතාවය මාරුකර සැහැල්ලු සහ නොඇලෙන ගතිය පෙන්නුම් කරයි. තවද විටමින් වල හා ශාක සාරවල ගුණාත්මක භාවය රඳාපවති.
Bio Oil European Parliament හා Council on Cosmetic Products වල ආරක්ෂක පරීක්ෂණ වලට භාජනය කර ඇත. විෂ රසායනික විද්‍යාවේ ආකෘතිය , රසායන නිර්මාණය, අඩංගු කිරීමේ ප්‍රමාණය සහ සම්පූර්ණ ප්‍රමාණය , දිනපතා නිරාවරණය වන සෑම කොටසක්ම තක්සේරු කර පාවිච්චියට සුදුසු බව ප්‍රකාශ කර ඇත. (ගර්භනී මව්වරුන්ටත් සුදුසුය)
අමුද්‍රව්‍ය
අමුද්‍රව්‍ය
Botanicals
Calendula Officinalis Flower Extract (Calendula Oil)
Lavandula Angustifolia Oil (Lavender Oil)
Rosmarinus Officinalis Leaf Oil (Rosemary Oil
Anthemis Nobilis Flower Oil (Chamomile Oil
Vitamins
Retinyl Palmitate (Vitamin A
Tocopheryl Acetate (Vitamin E
Oil base
Paraffinum Liquidum
Triisononanoin
Cetearyl Ethylhexanoate
Isopropyl Myristate
Glycine Soja Oil
Helianthus Annuus Seed Oil
Tocopherol
Bisabolol
Fragrance (Rose
Parfum
Alpha-Isomethyl Ionone
Amyl Cinnamal
Benzyl Salicylate
Citronello
Coumarin
Eugeno
Farnesol
Geraniol
Hydroxycitronellal
Limonene
Linalool
වර්ණය
CI 26100
නිෂ්පාදනය
නිෂ්පාදනය
Bio Oil නිෂ්පාදනය කරන්නේ ලෝක සෞඛ්‍ය සංවිධානයේ නිර්දේශවලට අනුකුලව cGMP (current Good Manufacturing Practice)යටතේය. සියලු අමුද්‍රව්‍ය ක්‍ෂද්‍ර ජීවී ආසාදනයන් සහ මිශ්‍ර කිරීම් නිෂ්පාදනයට පෙර පරික්ෂ කර ඇත. තවද සෑම නිෂ්පාදනය කරන කාණ්ඩයකම සාම්පලයක් පර්යේෂණාගාරය වල පරීක්ෂාකර අවුරුදු 5ක කාලයක් තිස්සේ රඳවා අධ්‍යනය කර ඇත.
සියළුම Bio Oil ඇසුරුම් ප්‍රතිචක්‍රීකරණය කල හැකි අතර සියළුම කඩදාසි ද්‍රව්‍ය තිරසාර වන කළමනාකරණ ක්රමවේදයන්ට අනුකුලව නිපදව ඇත.
Bio Oil නිෂ්පාදනයේදී හානිදායක පිට කිරීම, උප ද්‍රව සහිත හෝ දූෂන වතුර බැහැර කිරීම නොසිදු වේ.

සායනික පරීක්ෂණ
Scar study, 2010
Scar study, 2010
Trial centre
proDERM institute for applied dermatological research, Hamburg, Germany.
Objective
To assess the efficacy of Bio-Oil in improving the appearance of scars.
Sample
Subjects: 36 female participants of varying ethnicities. Age of participants: 18 to 65. Scar ages: newly formed to 3 years old. Scar locations: abdomen, leg, arm, neck, knee, trunk, upper body.
Methodology
Double-blind, randomised and placebo controlled. Subjects had matching scars or a scar large enough to allow a half-half scar application and intra-subject comparison. Product applied twice daily for 8 weeks, no additional massaging performed on the target area. Application performed under supervision at regular intervals. Assessments conducted at 0, 2, 4 and 8 weeks. Different scar parameters as defined in the Patient and Observer Scar Assessment Scale (POSAS) were evaluated.
Result
Bio-Oil is efficacious in improving the appearance of scars. A statistically significant result after only 2 weeks (day 15), evident in 66% of the subjects. After 8 weeks (day 57) 92% of subjects showed an improvement, with the extent of the improvement almost triple that at 2 weeks. A continuous improvement of POSAS over the duration of the study.
Scar study, 2005
Scar study, 2005
Trial centre
Photobiology Laboratory of the Medical University of South Africa.
Objective
To assess the efficacy of Bio-Oil in improving the appearance of scars.
Sample
Subjects: 24 participants, 22 female and 2 male. Age of participants: 18 to 60. Scar ages: newly formed to 3 years old. Scar types: range from minor burns to surgical scars (12 major scars, 14 minor scars - 1 participant had three scar sites).
Methodology
Single-blind (assessor), randomised and controlled. Paired study design allowing for intra-subject comparison. Subjects had matching scars or a scar large enough to allow application to half a scar. Product applied twice daily for 12 weeks to the targeted area. Application performed under supervision at regular intervals. Assessments conducted at 0, 4, 8 and 12 weeks.
Result
Bio-Oil improved the appearance of scars in both objective and subjective assessments. 65% of subjects recorded an improvement in appearance at 4 weeks.
Scar user trial, 2002
Scar user trial, 2002
Trial centre
Ayton Moon, Somerset , United Kingdom
Objective
To rate the ability of Bio-Oil to improve the appearance of scars, in an 82-person user trial.
Sample
Subjects: 82 participants including adults and children. Scar ages: newly formed to older than 10 years. Scar types: raised, flat and depressed scars, ranging from minor burns and grazes to surgical scars. Scar locations: various.
Methodology
Product applied 3 times daily for 4 weeks. Participants instructed to massage in a circular motion until product fully absorbed. Interviews conducted at 0, 2 and 4 weeks. Participants rated the improvement they noticed on a scale from 1 - 9 (1 representing 'no improvement' and 9 representing 'much improvement').
Result
82% of participants recorded an improvement in the appearance of their scars after 4 weeks.
Acne scar study, 2012
Acne scar study, 2012
Trial centre
Dept. of Dermatology, Peking University First Hospital, Beijing, China.
Objective
An exploratory study to assess the efficacy of Bio-Oil in improving the appearance of facial acne scars on Chinese subjects.
Sample
Subjects: 44 Chinese subjects with newly formed acne scars on the face (<1 year old). Bio-Oil treatment cell included 32 subjects and the no treatment cell included 12 subjects. Age of participants: 14 to 30.
Methodology
Randomised, controlled, efficacy grader-blinded. Subjects participated in an initial screening evaluation followed by a 1-week washout period. Product applied twice daily for 10 weeks. Application performed under supervision at regular intervals. Assessments conducted at 0, 4, 8 and 10 weeks included the following: Global scarring score (GSS) assessment by the investigator, measurement of acne scar colour / redness using a chromameter, measurement of sebum levels using a sebumeter, documentation of number of comedones and inflammatory lesions by a dermatologist. Subjects also completed self-assessment questionnaires at each visit.
Result
The best result of the clinical grading was in Bio-Oil's ability to reduce the erythema or redness of macular (flat) acne scars, with the overall skin becoming brighter. Results of the self-assessment questionnaire showed that more than 84% of subjects experienced an improvement in the overall condition of their acne scars and more than 90% experienced an improvement in scar colour. Acne count and sebum measurement results showed that using Bio-Oil does not cause or aggravate acne or increase sebum secretion.
Stretch mark study, 2010
Stretch mark study, 2010
Trial centre
proDERM institute for applied dermatological research, Hamburg, Germany.
Objective
To assess the efficacy of Bio-Oil in improving the appearance of stretch marks.
Sample
Subjects: 38 female participants of varying ethnicities. Age of participants: 18 to 65. Stretch mark causes: various (post pregnancy, weight gain or adolescent growth spurt). Stretch mark locations: abdomen, thigh and hips.
Methodology
Double-blind, randomised and placebo controlled. Subjects had matching stretch marks or a stretch mark large enough to allow a half-half stretch mark application and intra-subject comparison. Product was applied twice daily for 8 weeks, no additional massaging performed on the target area. Application performed under supervision at regular intervals. Assessments conducted at 0, 2, 4 and 8 weeks. Different scar parameters as defined in the Patient and Observer Scar Assessment Scale (POSAS) were evaluated.
Result
Bio-Oil is efficacious in improving the appearance of stretch marks. A statistically significant result after only 2 weeks (day 15), evident in 95% of the subjects. After 8 weeks (day 57) 100% of subjects showed an improvement, with the extent of the improvement more than double that at 2 weeks. A continuous improvement of POSAS over the duration of the study.
Stretch mark study, 2005
Stretch mark study, 2005
Trial centre
Photobiology Laboratory of the Medical University of South Africa.
Objective
To assess the efficacy of Bio-Oil in improving the appearance of stretch marks.
Sample
Subjects: 20 female participants. Age of participants: 18 to 55. Stretch mark location: abdomen.
Methodology
Single-blind (assessor), randomised and controlled. Paired study design allowing for intra-subject comparison. Subjects had bilateral abdominal stretch marks, enabling half-abdomen study design. Product applied twice daily for 12 weeks to the targeted area. Application performed under supervision at regular intervals. Assessments conducted at 0, 4, 8 and 12 weeks.
Result
Bio-Oil improved the appearance of stretch marks in both objective and subjective assessments. 50% of subjects recorded an improvement in appearance at 8 weeks.
Uneven skin tone study, 2011
Uneven skin tone study, 2011
Trial centre
Thomas J. Stephens & Associates, Inc., Texas, United States of America.
Objective
To evaluate the efficacy of Bio-Oil in improving the appearance of uneven skin tone and mottled pigmentation when used by women with mild to moderate photodamaged (ageing) skin on the face and neck.
Sample
Subjects: 67 female participants (of varying ethnicities) with clinically determined mild to moderate photodamage on the face and neck. Bio-Oil treatment cell included 35 subjects and the no treatment cell included 32 subjects. Age of participants: 30 to 70.
Methodology
Randomised, controlled, efficacy grader-blinded. Subjects participated in an initial screening evaluation followed by a 1-week washout period. Product applied to the face and neck twice daily for 12 weeks. Application performed under supervision at baseline visit. Clinical evaluations conducted at 0, 2, 4, 8 and 12 weeks. Subjects were clinically graded separately on the face and neck for uneven skin tone and mottled pigmentation.
Result
Bio-Oil is efficacious in improving the appearance of uneven skin tone and mottled pigmentation in photodamaged (ageing) skin. After 4 weeks a statistically significant result was achieved for both parameters on the face and neck. After 12 weeks 86% of subjects in the Bio-Oil treatment cell showed a statistically significant improvement in uneven skin tone on the face, 71% of subjects in mottled pigmentation on the face, 69% in uneven skin tone on the neck and 60% in mottled pigmentation on the neck.
Uneven skin tone study, 2005
Uneven skin tone study, 2005
Trial centre
Photobiology Laboratory of the Medical University of South Africa.
Objective
To assess the efficacy of Bio-Oil in improving the appearance of uneven skin tone.
Sample
Subjects: 30 female participants of varying ethnicities. Age of participants: 18 to 55. Pigmentation type: facial melasma.
Methodology
Single-blind (assessor), randomised and controlled. Paired study design allowing for intra-subject comparison. Subjects had bilateral pigmentation, enabling half-face/neck study design. Product applied twice daily for 12 weeks to the targeted area. Application performed under supervision at regular intervals. Assessments conducted at 0, 4, 8 and 12 weeks.
Result
Bio-Oil improved the appearance of uneven skin tone in both light and dark skin types. 93% of subjects recorded an improvement in appearance at 6 weeks. Clinician noted an equal improvement in both light and dark skin types from week 0 to 8. Clinician noted more improvement in dark skin types from week 8 to 12.
Ageing skin study, 2011
Ageing skin study, 2011
Trial centre
Thomas J. Stephens & Associates, Inc., Texas, United States of America.
අධ්‍යයනය: 1 මුහුණ සහ බෙල්ල
Objective
To evaluate the efficacy of Bio-Oil when used by women with mild to moderate photodamaged (ageing) skin on the face and neck.
Sample
Subjects: 67 female participants (of varying ethnicities) with clinically determined mild to moderate photodamage on the face and neck. Bio-Oil treatment cell included 35 subjects and the no treatment cell included 32 subjects. Age of participants: 30 to 70.
Methodology
Randomised, controlled, efficacy grader-blinded. Subjects participated in an initial screening evaluation followed by a 1-week washout period. Product applied to the face and neck twice daily for 12 weeks. Application performed under supervision at baseline visit. Clinical evaluations conducted at 0, 2, 4, 8 and 12 weeks. Subjects were clinically graded separately on the face and neck for the following efficacy parameters: overall appearance, fine lines, coarse wrinkles, mottled pigmentation, uneven skin tone, visual roughness/smoothness, tactile roughness/smoothness, firm appearance, and clarity (dullness).
Result
Bio-Oil is efficacious in improving the overall appearance of photodamaged (ageing) skin on the face and neck. After 8 weeks a statistically significant result was achieved for all clinically graded efficacy parameters. After 12 weeks 94% of subjects in the Bio-Oil treatment cell showed a statistically significant improvement in overall appearance on the face and 80% of subjects showed a statistically significant improvement in overall appearance on the neck.
Study 2: body
Objective
To evaluate the efficacy of Bio-Oil when used on the décolletage, lower leg and arm skin by women with mild to moderate photodamaged (ageing) skin.
Sample
Subjects: 67 female participants (of varying ethnicities) with clinically determined mild to moderate photodamage on the face and neck. Bio-Oil treatment cell included 35 subjects and the no treatment cell included 32 subjects. Age of participants: 30 to 70.
Methodology
Randomised, controlled, efficacy grader-blinded. Subjects participated in an initial screening evaluation followed by a 1-week washout period. Product applied to the décolletage, lower legs and arms twice daily for 12 weeks. Application performed under supervision at baseline visit. Clinical evaluations conducted at 0, 2, 4, 8 and 12 weeks. Subjects were clinically graded separately on the décolletage, lower legs and arms for the following efficacy parameters: overall appearance, crêpey texture, dryness/scaling, visual roughness/smoothness, and tactile roughness/smoothness.
Result
Bio-Oil is efficacious in improving the overall appearance of photodamaged (ageing) skin on the body. After 4 weeks a statistically significant result was achieved for all clinically graded efficacy parameters. After 12 weeks 89% of subjects in the Bio-Oil treatment cell showed a statistically significant improvement in overall appearance of the décolletage, lower legs and arms.
Dehydrated skin study, 2011
Dehydrated skin study, 2011
Trial centre
Photobiology Laboratory of the Medical University of South Africa.
Study 1
Objective
To assess the effect of a single application of Bio-Oil to improve stratum corneum (SC) barrier function and hydration.
Sample
Subjects: 40 female participants of varying ethnicities. Test site: test products applied to the volar forearm of all subjects.
Methodology
Assessment of skin hydration with a Corneometer as the primary measure, assessment of barrier function with a Vapometer as a secondary measure. Panellists washed their forearms with soap 2 hours before measurements were taken. Baseline instrumental measurements were taken. Bio-Oil and a reference oil were then applied to separate sites on the volar forearm of all subjects. Measurements were taken again immediately after product application as well as 2 hours later, before and after wiping the products off. A control untreated site was also measured at all time points.
Result
After immediate application, both oils reduced transepidermal water loss (TEWL) compared to the no treatment control. Increased skin capacitance values at the 2 hour pre-wipe time point indicated increased skin hydration for both oils. Two hours later, after wiping the oils from the skin's surface, Bio-Oil showed further increased TEWL values compared to the reference oil, indicating increased moisture release and therefore increased skin hydration.
Study 2
Objective
To assess the effect of twice daily application of Bio-Oil for moisturisation performance and relief of dry skin.
Sample
Subjects: 25 female Caucasian participants. Test site: test products applied to the outer, lower leg of all subjects.
Methodology
Soap was used to induce dry skin over a 7 day period. Bio-Oil and a reference oil were applied twice daily. Skin assessments were made on days 1 and 3. Visual evaluations were performed by a trained visual evaluator using a 2x magnifying lamp. A control untreated site was also evaluated at all time points.
Result
Both Bio-Oil and the reference oil improved skin dryness compared with the no treatment control. Bio-Oil was statistically superior on day 3. Significant improvements in visual appearance of skin sites treated with Bio-Oil confirmed its effectiveness in relieving dry skin.
Acnegenic test, 2006
Acnegenic test, 2006
Trial centre
Future Cosmetics, Pretoria, South Africa.
Objective
To test whether Bio-Oil is likely to cause acne and comedones (pimples).
Sample
Subjects: 21 participants, 17 female and 4 male of varying ethnicities, 50% prone to acne.
Methodology
Randomised and controlled. Product applied twice daily for 28 days. 3 areas evaluated: untreated area (negative control), area to which Bio-Oil was applied, and area to which acetylated lanolin alcohol was applied (positive control - a known acnegenic product). Test products applied to the upper back (scapular) region.
Result
Bio-Oil was found to be non-acnegenic and non-comedogenic. Area to which Bio-Oil was applied showed no significant difference to the untreated area. Positive control induced acne.
Sensitive skin test, 2006
Sensitive skin test, 2006
Trial centre
Future Cosmetics, Pretoria, South Africa.
Objective
To test whether Bio-Oil causes skin irritancy on subjects with sensitive skin.
Sample
Subjects: 21 participants. Age of participants: 18 to 65. Selection criteria: Subjects with known sensitive skin were selected and exposed to a positive control (lactic acid) to verify their sensitive skin status.
Methodology
Randomised and controlled. 3 areas were evaluated: area to which deionised water was applied (negative control), area to which Bio-Oil was applied, and area to which Sodium Lauryl Sulfate 1% solution was applied (positive control - a known skin irritant). Test products applied via a patch to the volar forearm and removed after 24 hours. Skin evaluated and reactions noted at 24, 48, 72 and 96 hours after application. Dermatologist present during the evaluations. Skin reactions rated on a scale from 0 – 4 (with 0 being no response and 4 being fiery redness).
Result
Bio-Oil was found to be a non-irritant product for subjects with sensitive skin. No subjects experienced any adverse reactions to Bio-Oil. Bio-Oil had an average reaction value of 0.03 over the period of 96 hours. Bio-Oil performed better than deionised water (negative control).
Absorption study, 2011
Absorption study, 2011
Trial centre
proDERM institute for applied dermatological research, Hamburg, Germany.
Study 1
Objective
To assess the rate of absorption of Bio-Oil after standardised application and rubbing in.
Sample
Subjects: 22 trained raters (21 female and 1 male). Test site: test products applied to the volar forearm of all raters.
Methodology
Double-blind, randomised and controlled. Bio-Oil and a reference oil were applied to assigned test areas on the volar forearms of raters. Raters performed 100 cyclic movements at a defined speed. Raters then rated the absorption of the products on a 5-point scale from 'very slow absorbing' to 'very fast absorbing'. Sebumeter measurements, to assess the amount of oil on the skin, were taken at two time points - before application and two minutes after product application.
Result
The absorbency of Bio-Oil into the skin was assessed as 'very fast' or 'fast' by the majority (77.3%) of trained raters. This was verified through instrumental measurement with sebumeter readings at the second time point showing that the amount of Bio-Oil left on the skin was significantly lower than compared with the reference oil.
Study 2
Objective
To assess the rate of absorption of Bio-Oil after standardised application and rubbing in.
Sample
Subjects: 100 participants (97 female and 3 male). Test site: test products applied to the volar forearm of all participants.
Methodology
Double-blind, randomised and controlled. Bio-Oil and a reference oil were applied to assigned test areas on the volar forearms of participants. Participants rubbed in the test product for 1 minute each. Participants then rated the absorption of the products on a 5-point scale from 'very slow absorbing' to 'very fast absorbing'.
Result
The absorbency of Bio-Oil into the skin was assessed as 'very fast' or 'fast' by the majority (72%) of participants.
Occlusivity study, 2008
Occlusivity study, 2008
Trial centre
Trial conducted by Prof. Dr. J Wiechers at Rigano Laboratories, Milan, Italy
Objective
To evaluate whether Bio-Oil demonstrates a similar occlusivity level to vernix caseosa. (Vernix caseosa, the creamy-white and viscous biofilm that envelopes a baby while it is in the womb, is widely considered by cosmetic scientists as the ‘gold standard’ in skin moisturisation because of its ideal occlusivity level.)
Methodology
Known quantities of water were placed in beakers covered with a semi-permeable membrane called Vitro-Skin™, which mimics the surface properties of human skin. Vernix caseosa and Bio-Oil were applied to the membrane and the rate of water loss from the beaker was measured over time. This was compared with the rate of water loss without any product on the membrane. The water vapour transfer rate for each product was calculated and expressed in g/m2/h.
Result
Bio-Oil demonstrated a very similar occlusivity level to vernix caseosa, with Bio-Oil registering 23.5 and vernix caseosa 27.2.

ගෞරව සම්මාන
සම්මාන බොහෝ නිර්දේශිතයි
වෛද්යවරුන් / ඖෂධවේදීන් / පවුල් සෞඛ්‍ය සේවිකාවන් විසින් නිර්දේශ කරනු ලබන කැළැල් හා සම ඇදිමෙන් පසුව ශේෂවු ඉරි සලකුණු සඳහා වූ නිෂ්පාදනය.
Australia, වෛද්‍ය සමීක්ෂණය (ACA Research HCP Study Jan 2019, 2019)
Australia, ඖෂධීය සමීක්ෂණය (ACA Research HCP Study Jan 2019, 2019)
Canada, වෛද්‍ය සමීක්ෂණය (EnsembleIQ Healthcare Group and RK Insights, 2019)
Canada, ඖෂධීය සමීක්ෂණය (EnsembleIQ Healthcare Group and RK Insights, 2019)
Germany, ඖෂධීය සමීක්ෂණය (BVDA / German Pharmacist Association, 2015)
Ireland, ඖෂධීය සමීක්ෂණය (3 Gem, 2015)
Italy, පවුල් සෞඛ්ය නිලධාරි සමීක්ෂණය (Millward Brown, 2014)
Kenya, ඖෂධීය සමීක්ෂණය (Consumer Insight, 2015)
New Zealand, වෛද්‍ය සමීක්ෂණය (Colmar Brunton, 2018)
South Africa, වෛද්‍ය සමීක්ෂණය (IPSOS, 2018)
South Africa, නාරිවේදී සමීක්ෂණය (IPSOS, 2018)
South Africa, පවුල් සෞඛ්ය නිලධාරි සමීක්ෂණය (IPSOS, 2018)
South Africa, ඖෂධීය සමීක්ෂණය (IPSOS, 2018)
United Kingdom, ඖෂධීය සමීක්ෂණය (3 Gem, 2018)
Zimbabwe, වෛද්‍ය සමීක්ෂණය (Marketers Association of Zimbabwe, 2016)
Zimbabwe, පවුල් සෞඛ්ය නිලධාරි සමීක්ෂණය (Marketers Association of Zimbabwe, 2016)
Zimbabwe, ඖෂධීය සමීක්ෂණය (Marketers Association of Zimbabwe, 2016)
අංක 1 විකිණීම
අංක 1 කැළැල් සහ සම ඉරි ඇඳීම් සඳහා වූ නිෂ්පාදනය
Australia (Aztec Segment and item list as defined by Aspen Pharmacare, based on AU Grocery & Pharmacy Scan combined data within Hand & Body Skin Care Database. September, 2017)
Belgium (IMS data Q2 2019 (value))
Botswana (Medswana (Pty) Ltd, 2016)
Canada (Nielsen MarketTrack. Specialty Creams, Lotions and Scar Treatments. National Grocery, Drug + Mass, 52 weeks ending Feb 3, 2018)
Finland (Pharmacy data and GFT retail data, value sales, 2016)
Germany (Nielsen IMS Health)
Hungary (IMS Health Pharmacy Survey Q1, 2016)
Ireland (IMS Firming & Anti-Stretch Mark Total value 52 week period July 18)
Italy (IMS Dataview Multichannel, Pharmacy + Parapharmacy + Corner Gdo, Reconstructed Class Anti-stretch marks (82F2A) + Scars (46A3), sell-out volume, rolling year ending in September 2018. )
Kenya (Consumer Insight, 2015)
Liechtenstein (IMS Health GmbH - Pharma Trend, Units & Sales Value, Sept 2017)
Malaysia (Nielsen, Scar & Stretch Mark, PM Drugstore/Pharmacy, January - June 2017)
Namibia (Geka Pharma (Pty) Ltd 2016 and Nampharm 2016)
Netherlands (IRI, YTD 52 2016)
New Zealand (IRI, National Combined MAT, October 2015)
Poland (IQVIA Poland Pharmascope 04/2019, 82F2 FIRMING&A-STRETCH PRODS, Value(PLN), MAT 04/2019 © 2019 IQVIA and its affiliates. All rights reserved.)
Portugal (39,4% Nº1 in Strech Market - Pharmacy only IQVIA Portugal July 2019)
Singapore (Nielsen, Scar & Stretch Mark, PM Drugstore/Pharmacy, 2016)
South Africa (Nielsen, Total Value ranking 52 week period ending 31 Jan 2018)
Swaziland (Swazi Pharm Wholesalers (Pty) Ltd, 2016)
Sweden (Nielsen Scanningdata, HPC, Other Skincare, Scars/Stretchmarks, MAT W52, 2018)
Switzerland (IMS Health GmbH - Pharma Trend, Units & Sales Value, Sept 2017)
Ukraine (PharmStandard)
United Kingdom (IRI Value Sales, Skincare Treatments category, Total UK, 52 weeks ending 1 Dec 2018)
Zimbabwe (Marketers Association of Zimbabwe, May 2016)

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